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The 28-day mortality rate was collected and calculated by follow-up of patients after intervention by telephone contacting their families

Ferroptosis serves as a promising target for CRC treatment Studies have demonstrated that ferroptosis is mainly regulated by the metabolism of amino acid, lipid and iron [26]

When IGF-1 receptors become less sensitive or when IGF-1 is not produced in sufficient quantities the entire somatotropic feedback system is affected