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Thus, the available scientific data on Semax's mechanisms may serve as a reference for the potential pharmacodynamics of N-Acetyl Semax Amidate: Semax enhances Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF) levels in the brain, which are neurotrophic factors facilitating neural survival and plasticity

J Exp Med 193(9):10051014 Kopp HG, Ramos CA, Rafii S (2006) Contribution of endothelial progenitors and proangiogenic hematopoietic cells to vascularization of tumor and ischemic tissue