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IV therapy is often used to treat dehydration, deliver medications, and provide nutritional support for patients who cannot adequately absorb nutrients through their digestive system

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Blood 82(10 Suppl 1), 1993

Do we need to reconsider the desirable blood level of vitamin B12

, diabetes, dysbiosis), chemical reactivity enables spontaneous modification, potentiated by glyoxalase system dysregulation: methylglyoxal is converted by glyoxalase 1 (GLO1) to lactoylglutathione (LGSH), which undergoes non-enzymatic acyl transfer to lysine residues ( Cellular lactate concentration directly modulates Kla levels (glycolytic inhibition suppresses Kla, while mitochondrial dysfunction or hypoxia enhances it) ( Figure 1 )

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