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A 2025 systematic review reported 7 of 12 maintained improvement beyond 6 months

However, larger studies are needed to confirm these benefits

If you experience severe pain, signs of infection (redness, warmth, swelling), or an allergic reaction (rash, itching, difficulty breathing), seek medical attention immediately

Menopause advocacy organizations, celebrity voices, and legislative action (including state-level menopause workplace accommodation bills) have pushed womens midlife health into the mainstream

All of these may contribute in some way to an imbalance

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