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Distribution of glutathione-S-transferase Glutathione S-transferases (GSTs) are the part of a superfamily of enzymes that play a key role in cellular detoxification and xenobiotic degradation

It acts in the lumen of the digestive tract, slowly binding to serine residues of the enzyme's active center, through a reversible covalent bond

Study Protocol The study is a single-center, double-blind, randomized, placebo-controlled 4-arm study design

It occurs when standing up quickly or changing positions

Of 305 metabolites analyzed by LC-MS, 53 showed significantly different abundance between DMF and PBS treatments (Fig

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