glutathione is made up of which amino acids - an overview Glutathione - The Tripeptide Antioxidant

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Oral bioavailability is expected to be negligible given the peptide's large size, and subcutaneous or intravenous delivery would likely be required for any human application

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doi:10.3390/nu11102362 7

This trend is in contrast to the rxYFP fusion constructs with mono- and dithiol variants of ScGrx1, which were shown to react more rapidly with GSSG when the second cysteinyl residue was replaced by serine (Table 1) 31