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The loading-then-maintenance approach comes from TB-500 protocols you hit it hard initially to get cells migrating, then taper to a maintenance frequency

[DOI] [PMC free article] [PubMed] [Google Scholar] 218.Tong Z-Z, Fang Z-M, Zhang Q, Zhan Y, Zhang Y, Jiang W-F, et al

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Energy-based devices, such as lasers, intense pulsed light, and radiofrequency devices, stimulate collagen remodeling and demonstrate significant therapeutic efficacy in skin rejuvenation [3,4]