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The effect of probiotic Lactobacillus casei Shirota on knee osteoarthritis: a randomised double-blind, placebo-controlled clinical trial

Conclusion The bottom line is that you should always check with your doctor before getting B12 injections

Researchers who reconstitute one vial at 10 mg/mL and the next at 5 mg/mL without adjusting their draw volume will get inconsistent doses

[PubMed: 26336917] 386

Stability at a glance: Lyophilized powder at minus 20C: stable for many months Bacteriostatic water solution at 2 to 8C: roughly 28 days Sterile water solution at 2 to 8C: a few days at most Single-use aliquots frozen at minus 20C: the longest option, but freeze only once Proper Documentation and Labeling Methods Good records turn a vial into reliable data

The exact amount is typically specified on the packaging