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Neurochem 114 , 14141423 (2010)

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it does not mean senolytics cause cancer, but it highlights that the biology of senescence is not uniformly harmful and that senolytic intervention requires careful therapeutic window definition

Gopinath PM, Saranya V, Vijayakumar S, Mythili Meera M, Ruprekha S, Kunal R, Pranay A, Thomas J, Mukherjee A, Chandrasekaran N

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Preliminary animal studies show that exercise in high-fat diet mice resulted in reduced hepatic 4-HNE levels and upregulation of anti-apoptotic protein expression (Merry and Ristow, 2016)