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If symptoms have not improved then LT4 therapy should generally be discontinued and the patient reviewed for other disorders

0% placebo) Headache (reported in at least 10% with bremelanotide) Local injection reactions: pain, redness, swelling Dizziness or lightheadedness Temporary increases in blood pressure Mild-to-moderate fatigue or malaise Rare but serious events include pronounced hypertensive episodes, severe allergic reactions, syncope, and less well-documented cardiac events in people with underlying heart disease

For long-term storage lasting several months or more, the freezer is the ideal place for lyophilized powder

10.1038/s41392-025-02124-y 31 GuoQ.JinY.ChenX.YeX.ShenX.LinM.et al (2024)