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Many patients experience moderate to severe pain, often described as stabbing or burning, which can persist for years after treatment cessation, significantly impairing their quality of life (Michalova et al., 2023

New Phytol 224:15691584 Maynard D, Kumar V, Spro J, Dietz K-J (2020) 12-Oxophytodienoic acid reductase 3 (OPR3) functions as NADPH-dependent , -ketoalkene reductase in detoxification and monodehydroascorbate reductase in redox homeostasis

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Additional Advantages: Elevated HGH levels also boost the production of insulin-like growth factor (IGF-1), which enhances nutrient transport to muscles, further speeding up muscle development

Individual variability: Genetic differences in receptor expression, enzyme activity, baseline cellular health create response heterogeneity