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Histological evaluations demonstrated more organized muscle architecture, while functional testing showed superior recovery of muscle performance compared with untreated controls (17)

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The presence of high serum bicarbonate could indicate chronic respiratory acidosis [typical of chronic obstructive pulmonary disease (COPD)] or metabolic alkalosis (secondary to vomiting, use of thiazide diuretics, or excess mineralocorticoids) (336)

However, there is a strong temperature dependence to n site concentrations