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Ultimately, we may find success in treating the rising tide of neurodegenerative disorders by addressing the hidden energetic and metabolic causes beneath the clinical waterline, rather than by focusing exclusively on the visible effects that naturally emerge, in time, above it
The role of TDP-43 mislocalization in amyotrophic lateral sclerosis
There are experimental data in mice that the antidepressant effects of NAC are blocked by AMPA antagonists [140], suggesting the involvement of AMPA receptors in the antidepressant-like effects of NAC
Similarly, zone 3 predominant hepatic steatosis is reported in adult NAFLD patients [28]
10.1089/ars.2021.0102 234 RamliF