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Your hydration levels, activity level, and overall metabolic health also play a role in how quickly you notice the benefits

Neuropathy causes nerve pain, including burning, tingling, and numbness

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When to seek medical help See a doctor promptly if you have spreading redness or warmth around the site, discharge or a fever, numbness or weakness that does not settle, or any swelling of the face, lips or throat or difficulty breathing, which can signal a rare allergic reaction and is a medical emergency

Because the vitamin deposits into muscle rather than entering the vasculature immediately, intramuscular delivery produces a sustained release effect