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However, if there are neurological symptoms that have arisen due to B12 deficiency, they could take up to three months to improve, with mild improvements occurring in the first six weeks

2-8C (refrigerator) for short-term Light: Protect from direct light Stability: Lyophilized peptides are generally stable for 12-24 months when stored appropriately Reconstituted Temperature: Store at 2-8C (refrigerator) do not freeze reconstituted peptide Stability: Use within 28-30 days when reconstituted with bacteriostatic water Note: If reconstituted with sterile water (without benzyl alcohol preservative), use within 24-48 hours and store under strict aseptic conditions These storage recommendations align with guidelines published by the National Research Council Canada and general pharmaceutical stability literature

Ensuring product stability is another key consideration

It is still preclinical, still mostly rodent, and still not translated to a human neurological trial, but it is mechanistically coherent across independent models

Drug pricing really is predatory

Giovannoni et al., 2022)