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PYM50028, a novel, orally active, nonpeptide neurotrophic factor inducer, prevents and reverses neuronal damage induced by MPP + in mesencephalic neurons and by MPTP in a mouse model of Parkinson's disease

10.3389/fnins.2020.589042 566 ZhouZ.LiJ.ZhangX

Ol, ethylhexylglycerin, benzyl salicylate, hexylcinnamyl, butylphenylmethylpropional, limonene, linalool.

Grotto D, Valentti J, Boeira S, et al

During mitophagy, mitochondria undergo characteristic morphological changes, including swelling, cristae rupture and vacuolization, which are distinct from the cristae reduction and fragmentation observed in ferroptosis (45)

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