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Full-length expanded ataxin-3 enhances mitochondrial-mediated cell death and decreases Bcl-2 expression in human neuroblastoma cells

Executive Summary Amended 2014

Reduced levels of GSH alter the redox state of the cell by decreasing the GSH/GSSG ratio and/or increasing ROS/RNS formation

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The p53 tumor suppressor is the guardian of the genome that participates in the control of cell survival and division under various stresses

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