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Why cysteine is the rate-limiting factor: The intracellular concentration of cysteine sits close to the Km value of GCL (0.1 to 0.3 mM), meaning the enzyme is operating near its saturation point under normal conditions

[DOI] [PubMed] [Google Scholar] 67.Pountos I, Panteli M, Lampropoulos A, Jones E, Calori GM, Giannoudis PV

Alternatively, in contexts such as the treatment of brain injuries and hypertension, injection has been the preferred method [29]

Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+. FEBS Letters

The highest score was reached with a ~4.5fold lower concentration of MitoQ in IMR-5/75 than in Be(2)-C cells, which seem to be more resistant to treatment ( Figures 2A, B )