Dermatol Res
However, several large randomized controlled trials, including the pivotal study by Moseley et al., and subsequent meta-analyses have demonstrated no long-term benefit over placebo or conservative therapy in terms of pain, function, or disease progression (Moseley et al., 2002)
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doi: 10.1002/art.40787 29
10.1016/S1054-3589(08)61084-4 Adv
It is worth noting that B OTS964 differs from intermediates previously reported during spliceosome activation 12,97,98,99 , in which both NTC and NTR complexes are either bound 12,97 or absent 98,99