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( D ) Mean relative PPP Flux in H441 cells treated with DMSO control or 1 M KEAPi (Davies et al, 2016) for 48 h and labeled with [1,2- 13 C]-glucose for 14.5 h

S-nitrosoglutathione S -nitrosoglutathione (GSNO) is the S -nitrosated derivative of GSH and is thought to be a critical mediator of the downstream signaling effects of NO ( S -nitrosation or S -glutathiolation (Hogg et al., 1997

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Methods Culture conditions Three strains of anaerobic bacteria, isolated by culturomics studies 21,22,23 and obtained from the Collection de Souches de lUnit des Rickettsies (CSUR, Marseille, France), were used for this study: Clostridium sporogenes CSURP3957, Clostridium subterminale CSURP3759 and Romboutsia lituseburensis CSURP3909