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Another important factor is the presence or absence of serum (as mentioned above) and biological contamination, which has significant effect particularly on immune cells

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Stimulation of whole blood cells from SZ patients with selective TLR agonists results in enhanced release of pro-inflammatory cytokines (including IL-1, IL-6, IL-8, and TNF-) (150), further supporting the role of TLRs in regulating neuroinflammation in schizophrenia

Full text: Gasmi, A., Nasreen, A., Lenchyk, L., Lysiuk, R., Peana, M., Shapovalova, N., Piscopo, S., Komisarenko, M., Shanaida, M., Smetanina, K., Antonyak, H., Fira, L., Lykhatskyi, P., Fira, D., & Bjrklund, G

It is about creating a solution at a specific concentration that makes accurate dosing possible