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10.1016/s0196-9781(02)00083-9 41 FuM.YuX.LuJ.ZuoY

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The class II HLA molecules that are associated with increased risk of T1D have been shown to bind peptides derived from the currently identified autoantigens described above and present these peptides to CD4 + T cells which then activate CD8 + cytotoxic T cells resulting in killing of islet cells