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Furthermore, mitochondrial damage is present early in disease course in TDP-43 A315T mice and increases motor neuron vulnerability (Gautam et al., 2019), consistent with dysregulation of the redox system early in neurodegeneration

Newman, H

Penicillamine can have severe side effects that include bone marrow suppression, blood disorders, kidney disease, and kidney failure (NLM 2012

After washing three times with PBS, fluorescence-conjugated secondary antibodies were added to the sections, which were incubated with secondary antibodies for 1 h at room temperature

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