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Interestingly, mice exposed to 4EPS exhibited anxiety-like behaviors, and treatments that promote oligodendrocyte differentiation were able to prevent the behavioral effects caused by 4EPS (Needham et al., 2022)

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Nevertheless, targeting the Wnt pathway alone presents significant challenges for cancer therapy, including poor drug response and toxic side effects (100)

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The main difference between glutathione and glutathione peroxidase is that glutathione is a tripeptide antioxidant found in cells, while glutathione peroxidase is a family of enzymes that help break down peroxides and protect cells from oxidative damage

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In addition, during liver zonation, knocking down LRP5 and LRP6 causes defective liver zonation in mice during liver regeneration

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[DOI] [PubMed] [Google Scholar] 107.Hosakote Y.M., Liu T., Castro S.M., Garofalo R.P., Casola A

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10.1002/ctm2.372 Clin Transl Med

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