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STAT are tyrosine kinases that can be activated by Janus kinase (JAK), causing their translocation into the nucleus to form dimers or heterodimers, resulting in the regulation of gene transcription

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Frontiers in Pharmacology, 16 , Article 1577628

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Papke RL, Stokes C, Damaj MI, Thakur GA, Manther K, Treinin M, Bagdas D, Kulkarni AR, Horenstein NA (2018) Persistent activation of 7 nicotinic ACh receptors associated with stable induction of different desensitized states