This concept is legitimate in the broader peptide literature, with some compounds demonstrating this kind of brain-targeted delivery via nasal administration
It also supports nervous system health and functionality, and it helps protect and repair damaged nerves
The Phase 2 trial enrolled participants with obesity and evaluated multiple dose levels over 48 weeks: 1 mg dose: 8.7% average body weight reduction 4 mg dose (escalated from 2 mg): 17.1% average body weight reduction 8 mg dose (escalated from 2 mg): 22.8% average body weight reduction 12 mg dose (escalated from 2 mg): 24.2% average body weight reduction Placebo: 2.1% average body weight reduction Those Phase 2 numbers were striking enough
The pen contains 200 units, with each unit containing 25 g of BPC-157 and 25 g of TB-500. Depending on the dosage, one pen lasts approximately 15 to 20 days
However, additional data was gathered with the knockout mice that indicated that while AOD9604 did not lead to significant weight loss or increase in lipolysis without the beta(3)-adrenergic receptors, there was an increase in energy expenditure and fat oxidation
This has led to the assumption that oral BPC-157 is interchangeable with injectable BPC-157 in humans