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Limitations of Commercial and Clinical Therapies In addition to small-molecule therapeutics, physical and biological approaches for treating hair loss have gained increasing prominence (Table 3)

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Pentadecapeptide BPC 157 Enhances the Growth Hormone Receptor Expression in Tendon Fibroblasts, Chang CH, Tsai WC, Hsu YH, Pang JH, Molecules, 2014 Nov 19;19(11):1906619077

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It may also have analgesic properties [36, 37]

Interestingly, DNA sequencing of non-malignant lung tissue revealed EGFR and KRAS mutations in 18% (54 out of 295) and 53% (43 out of 81) of samples, respectively, leading to the hypothesis that these mutations accumulate as part of the ageing process and that PM 2.5 promotes subsequent tumour formation in the at-risk epithelium harbouring these driver mutations 279