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Downstream genes regulated by the Nrf2/ARE axis include HO-1, NQO1, and iron metabolism-related proteins (FTH1, FTL, FPN1), etc.: HO-1 degrades pro-oxidative heme to produce bilirubin with iron-chelating activity, and NQO1 directly scavenges lipid free radicals

however, contraindications for the surgical procedure during which BSS PLUS is to be used should be strictly adhered to

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Prehabilitation programs integrating aerobic and resistance training have been shown to preserve lean muscle mass, improve surgical outcomes, and reduce systemic inflammation

T., Choi, B

In aggressive cancers (such as undifferentiated thyroid and pancreatic cancer), VSIG4-positive TAMS (VSIG4 + TAMs) regulate SPP1 through Kla modification, promoting neutrophil infiltration and impairing antigen-specific immunity, forming an immunosuppressive TME