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This event commonly occurs in conditions such as trauma, surgery, or shock, leading to compromised intestinal integrity

Hypochlorous acid (HOCl) is a highly reactive substance involved in the chlorination of lipids and protein residues

Thus, advanced experimental models, including 3D co-culture systems, organ-on-a-chip platforms, and humanized mouse models, should be prioritized to enhance the physiological relevance and translational potential of studies evaluating natural metabolite interventions

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Liver-specific knockout of ACC1 decreased hepatic lipid accumulation in mice and DNL in hepatocytes [58]

Additionally, L-GSH supplementation significantly reduced the burden of intracellular mycobacteria within in vitro granulomas generated from peripheral blood mononuclear cells (PBMCs) of T2DM subjects