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Homocysteine Metabolism in Pregnancy and Developmental Impacts

J Mol Neurosci 60:390404

10.1105/tpc.11.8.1381 Plant Cell 70 HubbertenH

Importantly, BBTMA occurs in an anaerobic environment, which suggests that it is catalyzed not by the CntA/B oxygenase, but rather by a novel oxygen-independent enzymatic pathway for the conversion of metabolites of the l-carnitine pathway to TMA

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Animal studies have reported observations of altered body composition and reduced adiposity in NNMT-inhibited models