Methanol and sodium dodecyl sulfate were used to improve the separation and reproducibility, and the LODs of L-carnitine and acetyl-L-carnitine were 3.0 and 5.0 M, respectively
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The virus supernatant was collected at 48 and 72 h post transduction, filtered through a cellulose acetate membrane (0.45 m, VWR, 28145481), and pooled together
Overexpression of CBS also has the downstream effect of increasing cysteine availability and the potential for a functional folic acid deficiency known as the folate trap in DS individuals (Pogribna et al , 2001)
L-Carnitine naturally occurs in the body as an amino acid derivative
[DOI] [PMC free article] [PubMed] [Google Scholar] 25.Ghobril C, Grinstaff MW