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Studies show the peptide increases dendritic spine density by 40-60% in treated brain regions, with formation of new functional synaptic connections confirmed by electrophysiological recordings demonstrating enhanced synaptic transmission and long-term potentiation

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More recently, Chuwen Feng and colleagues established a rat model of ME/CFS using a 35-day chronic multifactorial stress paradigm

The 2014 tendon fibroblast study reported increased growth hormone receptor expression after BPC-157 exposure, measured at mRNA and protein levels

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