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Second axis, extracellular matrix and tissue regeneration

Arch Intern Med 2005 Jan.;165(2):150156

Mean total Sharp score (mTSS) progression for the placebo group in this trial was small relative to what has been seen in RA (approximately 1 unit over 48 weeks), but this progression was clearly greater than in the etanercept group, where there was no mean total Sharp progression at both 24 and 48 weeks (Figure 7-5)

Herbal supplements and unregulated products present additional risks

Non-Hormonal : No PCT needed, safe for continuous use

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