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Diverse taxa of cyanobacteria produce - N -methylamino-l-alanine, a neurotoxic amino acid

A., Somogyi, R., Poulter, M

In vitro experiments reveal that GCCNPs could suppress the expression of VEGF in ARPE19 cells and HUVECs induced by H 2 O 2 , inhibit the vascular formation and migration of HUVECs induced by H 2 O 2 , and inhibit the oxidative reaction product 4-HNE and the chemokine stromal-derived factor-1 (SDF-1) and its receptor CXCR4 in laser-induced choroidal neovascularization C57 model mice following intravitreal injection

This approach also improves routine consistency, which is more important than perfect timing

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Nov 1 2020;26(6):942-960