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Thiamine production can also be hindered by thiaminases, "enzymes that catalyze the break down of thiamine" - Webster Merriam

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Set expectations

Another important point to make is that unlike other vitamins, the absorption of B12 is dependent on a protein called intrinsic factor that is produced in your stomach

The addition simply adds other compounds to your regimen

TB-500 promotes the growth of new capillaries into the injury zone, improving the local environment for repair