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Hepatoprotective activity of Centaurium erythraea on acetaminophen-induced hepatotoxicity in rats

To date, herbal drug regulation, differ across countries ( Several studies, conducted mainly in East Asia, have shown that several plants and their compounds have positive effects on MS (Yadav et al., 2010

Neuropharmacology (2015) 97:4657.10.1016/j.neuropharm.2015.04.037 55 ShihR-HWangC-YYangC-M

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The mechanism may be caused by aberrant hepatic lipid-producing pathways and mTORC2-mediated transcriptional activation of SREBP-1c, underscoring the need for combined lipid-lowering therapy

A thicker needle (a lower gauge number) creates more trauma at the injection site, which can be a confounding variable in itself, especially in studies looking at healing or inflammation