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Although chronic kidney disease is not diagnosed until the eGFR reaches 60 mL/min, being able to detect earlier, less-significant decrements in kidney function is important, as the period of subclinical kidney dysfunction before overt kidney disease can be diagnosed based on creatinine may last one to two decades (Rush-Monroe 2013

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144 The ratio between the active ingredients of the medical device is 1:20:40 for CS, HA, and aluminum hydroxide, respectively