This direct administration is particularly beneficial for individuals with malabsorption issues, such as those with pernicious anemia, Crohn's disease, or celiac disease
In that context, it is instructive to analyse the lead up to the Fourth Memorandum on Strategic Planning in the Netherlands (1988)
In a recent review (2018) by the famous Cochrane Institute, it was reported that studies which had been published on this topic only provided very low-quality evidence that oral B12 is as efficacious as intramuscular B12
Attempting to use it without a proper medical evaluation is risky
In rare cases, side effects may include allergic reactions, swelling, chest tightness, or difficulty breathing
Reconstitution, storage, administration, and cycling all affect outcomes, and errors in any of these areas can compromise both safety and efficacy