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To counter drug resistance commonly encountered in GBM treatment, stimuli-responsive drug carriers that release therapeutic agents in response to specific tumor environment triggers are essential

Pancharuniti N, Lewis CA, Sauberlich HE, Perkins LL, Go RCP, Alvarez JO, Macaluso M, Acton RT, Copeland RB, Cousins AL, Gore TB, Cornwell PE, and Roseman JM (1994)

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That could be significant margin increases and, thus, stock price increases for the companies that can achieve this