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Importantly, blockade of cysteine-dependent glutathione synthesis was sufficient to reverse melatonin-mediated suppression of ILC2 cytokine production ( Figures 6J, K )

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and de Mattos Zeri, Ana Carolina (2015)

This can most commonly be seen in polycystic ovarian syndrome (PCOS) or endometriosis

Biomolecules 5:318342 Baudouin-Cornu P, Lagniel G, Kumar C, Huang ME, Labarre J (2012) Glutathione degradation is a key determinant of glutathione homeostasis