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MORE: Blood in Urine Summary Bright yellow urine is often a side effect of vitamin B2 supplementation or dehydration

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This results in the activation of mast cells and the release of inflammatory mediators, including histamine, leukotrienes, and others, which can manifest as pruritus, urticaria, angioedema, bronchospasm, vomiting, and hypotension

There is no hard-and-fast amount thats recommended, but upwards of 1,000 mg a day appears to be safe

Some begin therapy soon after injury or surgery (pending guidance), while others use it for chronic or overuse injuries

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