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Apamin is a selective inhibitor of small-conductance calcium-activated potassium (SK) channels, exhibiting nanomolar or even subnanomolar affinity

Research indicates Dihexa can restore cognitive function in animal models of cognitive impairment including scopolamine-induced memory deficits and age-related cognitive decline, suggesting potential applications for neurodegenerative disease research

The longer effective tissue exposure is consistent with the actin-sequestration mechanism, which depends on intracellular accumulation rather than transient extracellular signaling

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Results In general, the retrobulbar L-NAME application procedure induces only short-lasting mild increase of intraocular pressure

The test involves a simple blood draw, which may cause mild discomfort or a slight pinch at the puncture site