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As the most abundant intracellular antioxidant, glutathione plays a central role in cellular redox homeostasis and has been extensively characterised in biochemical, toxicological, and pharmacological research over several decades

Preliminary research also suggests that boosting NAD may improve body composition

PLoS One 8 (4), e61315

Upregulation of TXNIP by ROS stimulated the NLRP3 inflammasome, which activated the protease caspase-1 to facilitate the release of inflammatory cytokines such as interleukin-18 (IL-18) and interleukin-1 (IL-1) and triggered inflammatory responses