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As expected, exposure to HnB mainstream led to a significant induction of CYP1A1, including protein expression, CYP2B1/2 (activating olefins and halogenated hydrocarbons) and CYP2A1/2 (activating, polychlorinated biphenyls, aromatic amines, PAHs, and alkylnitrosamines)

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According to the transcripts per million reads (FPKM) method, the gene expression levels of transcript were calculated to further identify the differential expression genes (DEGs) between two groups