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Some cell-types are much less sensitive to doxorubicin-induced GSH depletion

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Jain S, Su YH, Su YP, McCloud S, Xue R, Lee TJ, Lin SC, Lin SY, Song W, Steffen JD, Hu CT

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in fact, they induce the release of calcium from cellular stores with the consequent activation of kinases, such as protein kinase C (PKC), thereby playing important roles in the proliferation of cancer cells 18

The system was controlled using MassHunter 12 software (Agilent, Palo Alto, CA, USA)