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Experimental studies suggest that DSIP may interact with multiple signalling mechanisms, including NMDA receptorrelated pathways and MAPK-associated signalling cascades, with observed effects dependent on concentration, exposure duration, and experimental context

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Women with neurological symptoms, severe anaemia, or confirmed deficiency require prompt medical assessment and specialist referral where appropriate

Reported biochemical potency against human NNMT is in the low-micromolar range with cellular EC values in the low-micromolar range for suppression of 1-MNA and lipogenesis, with selectivity over related methyltransferases and NAD-salvage enzymes [1,6,7]

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