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Microsomal prostaglandin E synthase-1 is overexpressed in inflammatory bowel disease

Semaglutide (Wegovy) is also used to treat metabolic dysfunction-associated steatohepatitis (MASH), without cirrhosis of the liver

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Glutathione plays a key supporting role in this process by helping to neutralise and prepare certain oestrogen metabolites for safe removal

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This combined evidence suggests that they might synergize during AD to protect the CNS against infection