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Together, these findings demonstrate how polyphenols act on critical immune and inflammatory pathways, offering a mechanistic basis for their development as complementary or alternative therapeutic strategies in psoriasis management [70,71,72,73,74,75,76,77,78,79,80,81,82,83,84,85]

For example, it has been shown that IPF patients who have a specific genotype in the mucin MUC5B gene polymorphism (see above) experience slower decline in FVC and significantly improved survival

Permanent effects are rare and usually linked to misuse or unregulated products

& Dharmani, C

Plant Sci 211:7791

Ero1 can efficiently drive the oxidation of RNase A through PDI in the absence of GSH or GSSG, or even in the presence of excess GSH (Tu et al , 2000), indicating that oxidative protein folding proceeds through the direct transfer of oxidizing equivalents between PDI and Ero1