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A deeper understanding of these interconnected metabolic networks clarifies the critical role of ferroptosis in OA progression and lays a robust foundation for integrated therapeutic strategies targeting both metabolic reprogramming and ferroptosis

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Rabbani P, Takeo M, Chou W, Myung P, Bosenberg M, Chin L, Taketo MM, Ito M (2011) Coordinated activation of Wnt in epithelial and melanocyte stem cells initiates pigmented hair regeneration

For example, while quercetin supplementation selectively enriched Akkermansia muciniphila and reduced uremic toxins in murine models (211), human bioavailability is 3 mL/min/1.73 m 2 /year or persistent macroalbuminuria)