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Copper uptake into cells is predominantly mediated by copper transporter 1 (CTR1), also known as solute carrier family 31 member 1 (SLC31A1) (Kuo et al., 2001)
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Patients with active cancer should discuss BPC-157 with their oncologist, as its angiogenic and growth factor properties could theoretically be contraindicated in the setting of active malignancy
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Among the UPR proteins, XBP1 is one of the most important regulators of lipogenesis and VLDL secretion, via directly and indirectly controlling the expression of critical genes involved in fatty acid synthesis [60]
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